AI overview
AI generated. Not medical advice.What it's for
Methylation and homocysteine metabolism, energy production, nervous system support
Who it may fit
Adults with busy schedules seeking convenient methylated B vitamins or those with low intake of folate-rich and B12-rich foods.
Key actives per serving
- Folate (as 5-Methyltetrahydrofolate, Quatrefolic): 1,360 mcg DFE (340% DV)
- Vitamin B12 (as methylcobalamin): 1,000 mcg (41667% DV)
- Vitamin B6 (as pyridoxal-5-phosphate): 15 mg (882% DV)
- Riboflavin (as riboflavin 5'-phosphate): 30 mg (2308% DV)
- Betaine (trimethylglycine): 600 mg
How to take
Adults take 2 capsules once daily with 8 oz of water, with or without food; if you experience stomach sensitivity, taking with a meal may be more comfortable.
Diet / Allergen fit
Non-GMO; Soya-free; Dairy-free; Gluten-free
Ingredients explained
Folate (as 5-Methyltetrahydrofolate, Quatrefolic)
5-MTHF is the bioactive folate form that donates methyl groups for one‑carbon metabolism, helping convert homocysteine to methionine and supporting DNA synthesis.
Caution: High-dose folate may mask low vitamin B12 status; consider consistent B12 intake if diet is low in animal foods.
Vitamin B12 (as methylcobalamin)
Methylcobalamin acts as a cofactor for methionine synthase in methylation pathways and supports red blood cell formation and nervous system function.
Caution: Very high intakes can cause acne-like skin reactions in some people; separate from acidic beverages if sensitive to stomach upset.
Vitamin B6 (as pyridoxal-5-phosphate)
Pyridoxal-5-phosphate functions as a coenzyme in amino acid metabolism and neurotransmitter synthesis and supports homocysteine metabolism with folate and B12.
Caution: Excessive long-term B6 intake may cause tingling or numbness; follow suggested use.
Riboflavin (as riboflavin 5'-phosphate)
Riboflavin 5'-phosphate provides FAD and FMN coenzymes that help enzymes produce cellular energy and regenerate antioxidants.
Caution: May cause bright yellow urine due to riboflavin excretion; this is harmless.
Betaine (trimethylglycine)
Betaine donates methyl groups to support the remethylation of homocysteine to methionine via the BHMT pathway.
Caution: May cause mild stomach upset in some individuals; take with water and consider taking with food if sensitive.
How they work together
5-MTHF and methylcobalamin provide key methyl donors and cofactors for methionine synthase, while betaine offers an alternate methylation route via BHMT. Vitamin B6 and riboflavin supply active coenzymes that facilitate amino acid processing and energy metabolism, supporting the broader one‑carbon and redox systems.
Safety and tips
Label Warning: Do not exceed the recommended dose. Pregnant or nursing individuals, children under 18, and those with a known medical condition should consult a doctor before use. Stop use two weeks before surgery. Use caution if you have allergies or sensitivities to any listed ingredients.
Who should be cautious: People with a known medical condition, those scheduled for surgery, and individuals who are pregnant, nursing, or under 18 should seek medical advice before use. Those with allergies or sensitivities to capsule or filler ingredients should take care.
Storage: Store in a cool, dry place. Keep out of reach of children and pets.
iHerb Quality Promise
This product is guaranteed authentic and backed by our easy returns and refunds policy. Details
Magnesium and B vitamins may support energy production and reduce fatigue, promoting overall vitality and well-being.
AI generated. Not medical advice.
Overview
- 5-MTHF
- betaine
- Riboflavin
- B2, B6, B9, B12
- Beyond Vitamins®
- Food Supplement
- B-Complex
- Quatrefolic®
- Methylcobalamin
- Non-GMO
- Soya-free
- Dairy-free
- Gluten-free
- cGMP-certified manufacturing
- Feel different
Codeage methyl folate B Complex+ offers a blend of folate as 5-MTHF, riboflavin vitamin B2, vitamin B6, vitamin B12 in its methylated form, and betaine for a comprehensive vitamin B complex formula. 2-month supply.
- Codeage methyl folate B Complex+ formula boasts 1360 mcg of folate vitamins as 5-MTHF folate per serving, using Quatrefolic® 5 methylfolate and glucosamine salt.
- This advanced formula also features Riboflavin (30 mg Riboflavin 5’-Phosphate - vitamin B2), 15 mg of vitamin B6, and 1000 mcg of vitamin B12 methylcobalamin per serving. These vitamins B2, B6, and B12 offer a comprehensive B vitamin combination.
- These methylated vitamins harmoniously combine 600 mg of betaine (trimethylglycine TMG) with Vitamins B6 and B12 in their superior phosphorylated forms.
Specifications
- First available: 03/2023
-
Delivery weight:
0.11 kg
- Product Code: AGE-00859
- UPC: 853919008595
- Package quantity: 120 Count
- Dimensions: 9.3 x 6.5 x 6.5 cm , 0.11 kg
Suggested use
Adults take 2 capsules daily, or as recommended by your healthcare practitioner, with 8 ounces of water or your favourite beverage. May be taken with or without food.
Other ingredients
Methylcellulose capsule, microcrystalline cellulose, l-leucine.
Made in the USA with globally sourced ingredients.
Warnings
Do not exceed recommended dose. Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a doctor before using this or any dietary supplement. Discontinue use two weeks before surgery. Please use caution if you have allergies or sensitivities to any of the listed ingredients.
Store in a cool, dry place. Do not use if the product has been opened or tampered with in any way. Keep out of reach of children and pets.
Disclaimer
While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally be despatched with alternative packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and do not rely solely on the information provided by iHerb. This website has been machine translated as a courtesy to customers. iHerb does not represent or warrant that the translations are complete or error-free and iHerb is not responsible for any translation errors or omissions.
| Supplement information | ||
| Serving Size:2 Capsules | ||
| Servings Per Container:60 | ||
| Amount per serving | %DV | |
| Riboflavin (as Riboflavin 5'-Phospate) | 30 mg | 2,308% |
| Vitamin B6 (as Pyridoxal-5-phosphate) | 15 mg | 882% |
| Folate (as Quatrefolic® [6S]-5-Methyltetrahydrofolate, glucosamine salt) | 1,360 mcg DFE | 340% |
| Vitamin B12 (as methylcobalamin) | 1,000 mcg | 41,667% |
| Betaine (as Trimethylglycine) | 600 mg | ** |
| Daily Value (DV) not established. | ||